Axolotls and Organ Renegration

In News: Scientists study the tragedy of the axolotl mutant and its mystery gene

About Axolotls and Organ Renegration:

• The axolotl is a species of salamander (lizard-like amphibians) originally found in Lake Xochimilco, near Mexico City.
• Even though they are amphibians, axolotls remain aquatic throughout their lives and are now almost extinct in the wild.
• They are known for their exceptional ability to regenerate organs and can regrow not only limbs but also complex organs such as the heart, spinal cord, and eyes.
• Axolotls possess cells called blastemal cells, which are responsible for initiating the regeneration process.
• When an organ is damaged or lost, these blastemal cells are activated and undergo cell division to form new tissue.
• The regenerative process involves the reorganization of cells and the growth of new blood vessels, nerves, and other structures.
• Unlike in humans, axolotls can regenerate without scarring, resulting in the restoration of both form and function.
• Research on axolotls' regenerative abilities offers insights into potential applications for human tissue regeneration and eventually human organ regeneration.
• Axolotls' regenerative abilities have the potential to revolutionize the field of regenerative medicine, organ transplantation and regenerative therapies.

https://www.thehindu.com/sci-tech/science/axolotl-o-gene-humphrey-briggs-limb-regeneration/article66883895.ece